One or more photo(s) has been virtually staged. Tucked away on more than 2.5 acres less than a mile from UF and Shands, this one of a kind property offers the serenity of a nature preserve right in the heart of Gainesville. Perched high above Hogtown Creek, the home captures sweeping, tree top views and complete privacy a rare combination of acreage, location, and natural beauty. Step inside to a dramatic two story great room wrapped in cedar batten and board with a striking Spade stone fireplace that anchors the space and frames the view beyond. Walls of windows blur the line between indoors and out, filling every room with light and a connection to the surrounding preserve. The main level features a formal living room with bay windows, a spacious dining room with custom built ins, and an island kitchen with double ovens and breakfast area opening to the pool deck. The primary suite is a peaceful retreat overlooking the pool and wooded backdrop, while upstairs offers five additional bedrooms (two of which have ensuite bathrooms) plus an office and game room plenty of space for family, guests, or multi generational living. Recent updates include a NEW 2024 roof, newer water heaters, fresh interior and exterior paint, and luxury vinyl flooring. Outdoors, enjoy the 30,000 gallon pool, multiple decks, and direct access to the creek below. With timeless design, enduring craftsmanship, and unmatched privacy, this Shands Woods retreat blends the best of nature and convenience minutes to UF, Shands, the VA, and downtown, yet worlds away from it all.